Blood Handling
What Temperature for Platelet Storage? Why Not Refrigerate?
Updated 2026-06-13 · Hotech Technical Team
In short
Platelets are generally stored at 20–24°C (near room temperature) with continuous, gentle agitation. This range maintains platelet viability and hemostatic function; refrigerating them like red cells reduces post-transfusion circulation survival, so platelets are kept at constant temperature with agitation, typically for a shorter shelf life.
Why 20–24°C
- This range supports platelet metabolism and function; refrigerated platelets are cleared from the body faster after transfusion, reducing circulation survival.
Why agitation is needed
- Continuous gentle agitation maintains gas exchange in the bag and prevents settling and aggregation.
Shelf life and QC
- Because room-temperature storage carries bacterial-growth risk, platelet shelf life is usually shorter than red cells, requiring strict QC and temperature monitoring.
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FAQ
Why not refrigerate platelets?
Refrigerated platelets are cleared faster after transfusion with lower survival, so they are kept at 20–24°C with agitation.
How long can platelets be stored?
Due to bacterial-growth risk at room temperature, shelf life is usually shorter than red cells and requires strict QC; follow each blood bank's policy.
Must platelets be agitated?
Yes — continuous gentle agitation helps maintain gas exchange and prevent aggregation.